The Etiology Of Hypertension
 

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Etiology of secondary hypertension hypertension complication

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Only in a small minority of patients with elevated arterial pressure, can a specific cause be identified. hypertension complication These individuals will probably have an endocrine or renal defect that, if corrected, could bring blood pressure back to normal values.

Renal hypertension  hypertension complication
Hypertension produced by diseases of the kidney. This includes diseases such as polycystic kidney disease or chronic glomerulonephritis. Hypertension can also be produced by diseases of the renal arteries supplying the kidney. This is known as renovascular hypertension; hypertension complication it is thought that decreased perfusion of renal tissue due to stenosis of a main or branch renal artery activates the renin-angiotensin system.
Adrenal hypertension
Hypertension is a feature of a variety of adrenal cortical abnormalities. hypertension complication In primary aldosteronism there is a clear relationship between the aldosterone-induced sodium retention and the hypertension.
In patients with pheochromocytoma increased secretion of catecholamines such as epinephrine and norepinephrine by a tumor hypertension complication (most often located in the adrenal medulla) causes excessive stimulation of [adrenergic receptors], which results in peripheral vasoconstriction and cardiac stimulation. This diagnosis is confirmed by demonstrating increased urinary excretion of epinephrine and norepinephrine and/or their metabolites hypertension complication (vanillylmandelic acid).
Coarctation of the aorta
Diet
The North American diet that is high in fat and salt has been proven to exacerbate hypertension. hypertension complication A study in the U.S. found that patients placed on a strict vegetarian diet showed a significant benefit to their condition over the one year. Certain medications, especially NSAIDS (Motrin/ibuprofen) and steroids can cause hypertension. hypertension complication Imported licorice (Glycyrrhiza glabra) inhibits the 11-hydroxysteroid hydrogenase enzyme (catalyzes the reaction of cortisol to cortison) hypertension complication which allows cortisol to stimulate the Mineralocorticoid Receptor (MR) which will lead to effects similar to hyperaldosteronism, which itself is a cause of hypertension. hypertension complication [Reference: Harrisons Internal Medicine, online edition (2007-04-14)]
Age
Over time, the number of collagen fibers in artery and arteriole walls increases, hypertension complication making blood vessels stiffer. With the reduced elasticity comes a smaller cross-sectional area in systole, and so a raised mean arterial blood pressure.

The Etiology Of Hypertension Free




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Sildenafil May Help In Complication After Pulmonary Embolism (Medical News Today)
About 4% of patients with persistent symptoms after pulmonary embolism develop hypertension in the pulmonary circulation, also called pulmonary hypertension. This is a serious complication leading to disabling symptoms, impaired exercise capacity and increased mortality if left untreated. [click link for full article]

Millennium Reports Outstanding Third-Quarter Results Driven by VELCADE(R) (Bortezomib) for Injection Sales (FinanzNachrichten)
CAMBRIDGE, Mass., Nov. 1 /PRNewswire-FirstCall/ -- Millennium Pharmaceuticals, ( Nachrichten / Aktienkurs ) Inc. today announced its financial and operational results for the third quarter of 2007. The Company raised its full-year 2007 financial guidance for the second time this year.

Millennium Reports Outstanding Third-Quarter Results Driven by VELCADE(R) (Bortezomib) for Injection Sales (PR Newswire via Yahoo! Finance)
Millennium Pharmaceuticals, Inc. today announced its financial and operational results for the third quarter of 2007.

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