The Etiology Of Hypertension
 

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Etiology of secondary hypertension hypertension kidney

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Only in a small minority of patients with elevated arterial pressure, can a specific cause be identified. hypertension kidney These individuals will probably have an endocrine or renal defect that, if corrected, could bring blood pressure back to normal values.

Renal hypertension  hypertension kidney
Hypertension produced by diseases of the kidney. This includes diseases such as polycystic kidney disease or chronic glomerulonephritis. Hypertension can also be produced by diseases of the renal arteries supplying the kidney. This is known as renovascular hypertension; hypertension kidney it is thought that decreased perfusion of renal tissue due to stenosis of a main or branch renal artery activates the renin-angiotensin system.
Adrenal hypertension
Hypertension is a feature of a variety of adrenal cortical abnormalities. hypertension kidney In primary aldosteronism there is a clear relationship between the aldosterone-induced sodium retention and the hypertension.
In patients with pheochromocytoma increased secretion of catecholamines such as epinephrine and norepinephrine by a tumor hypertension kidney (most often located in the adrenal medulla) causes excessive stimulation of [adrenergic receptors], which results in peripheral vasoconstriction and cardiac stimulation. This diagnosis is confirmed by demonstrating increased urinary excretion of epinephrine and norepinephrine and/or their metabolites hypertension kidney (vanillylmandelic acid).
Coarctation of the aorta
Diet
The North American diet that is high in fat and salt has been proven to exacerbate hypertension. hypertension kidney A study in the U.S. found that patients placed on a strict vegetarian diet showed a significant benefit to their condition over the one year. Certain medications, especially NSAIDS (Motrin/ibuprofen) and steroids can cause hypertension. hypertension kidney Imported licorice (Glycyrrhiza glabra) inhibits the 11-hydroxysteroid hydrogenase enzyme (catalyzes the reaction of cortisol to cortison) hypertension kidney which allows cortisol to stimulate the Mineralocorticoid Receptor (MR) which will lead to effects similar to hyperaldosteronism, which itself is a cause of hypertension. hypertension kidney [Reference: Harrisons Internal Medicine, online edition (2007-04-14)]
Age
Over time, the number of collagen fibers in artery and arteriole walls increases, hypertension kidney making blood vessels stiffer. With the reduced elasticity comes a smaller cross-sectional area in systole, and so a raised mean arterial blood pressure.

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Hypertension
The most common cause of secondary hypertension is kidney disease. ... kidneys, or arteries, and could lead to heart attacks, strokes, or kidney failure. ...

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Scientists find way to 'switch off' hypertension (IANS via Yahoo! India News)
New York, Nov 2 (IANS) In a finding that has implications for the treatment of hypertension, researchers have identified what they believe is the 'master switch' that regulates blood pressure.

Scientists find way to 'switch off' hypertension (EARTHtimes.org)
New York, Nov 2 - In a finding that has implications for the treatment of hypertension, researchers have identified what they believe is the 'master switch' that regulates blood pressure.

Master Switch That Regulates Blood Pressure Identified By OHSU Researchers (Medical News Today)
A team of Oregon Health & Science University researchers studying a rare form of hypertension has identified the mechanism by which they believe a protein complex in the kidney operates as a master switch that regulates blood pressure, a finding that has broad implications for the treatment of more common forms of hypertension.The team led by David H. Ellison, M.D. [click link for full article]

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